At Week 26, the primary HbA1c endpoint was missing for 5.6%, 8.6% and 8.6% of patients randomized to placebo, semaglutide tablets 7 mg and semaglutide tablets14 mg, respectively
[2] [14] Dehydration secondary to gastrointestinal adverse effects could potentially exacerbate MS-related fatigue and may increase risk of acute kidney injury, though this relationship has not been formally studied
(2) protein timing may be suboptimal ensure intake is spread across 34 meals not concentrated in one or two
Q4 2026 (earliest): NDA filing with the FDA for the weight-management indication
The primary endpoint was the percent change in body weight over the 72 weeks, and the key secondary endpoints were a weight reduction of at least 10%, 15%, 20%, and 25% and a change in waist circumference
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